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[dramatic music]
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- Tonight, the suspicious
death of a legendary leader.
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- Alexander did more in 10 years
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than other people
do in lifetimes.
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- He basically creates
the largest empire
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the world has ever seen.
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- After all these years of
campaigning and severe wounds,
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he makes it back to Babylon
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and then suddenly dies.
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- Historians are still baffled
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by what happened in the last
few weeks of Alexander's life.
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- He begins to see strange
omens that convince him
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that his days are numbered.
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- Alexander sees
enemies everywhere
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and he drowns his fears in
the bottom of a wine cup.
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- Now we'll explore
the top theories
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surrounding the unsolved death
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of one of history's
most celebrated figures.
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- It would only take a small
drop in his cup of wine
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for it to all be over.
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- Alexander fails
to name a successor
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and that may have
cost him his life.
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- Whatever killed Alexander,
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it sure doesn't look
like a natural death.
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- Who or what killed
Alexander the Great?
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[uplifting music]
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323 BCE,
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Alexander the Great lies
on his deathbed in Babylon,
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present-day Iraq.
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His generals file past him
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for a final glimpse
of their king.
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After all they've achieved,
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it's hard to believe
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that their seemingly
invincible leader is dying.
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- [Darel] Alexander was surely
the most famous person
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of ancient times.
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He was feared, he was powerful,
and he could be brutal,
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but he was also highly
educated and philosophical,
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and that's what made him
such an interesting figure.
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- [Robert] Alexander the Great
comes
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from the Greek
kingdom of Macedonia,
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and during the
fourth century BCE,
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he basically rules over all of
the city-states in this area.
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- [Hugo] The biggest arch
rival of the Macedonians
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is the Persian Empire.
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At this time, the Greek
city states are reeling
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from a violent attack from the
Persians a few years earlier,
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and so Alexander is
now out for revenge.
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- [Laurence] His plan,
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to assemble the largest
army Greece has ever seen
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and march straight
into enemy territory.
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- One thing that a lot of
people might not realize
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is that Alexander,
at least initially,
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is actually the underdog.
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Although he has a
highly trained army,
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they are tiny in comparison
to the Persian army.
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- [Hugo] What Alexander
has in his favor
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is that he's an expert
at rallying troops
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from all across
these Greek kingdoms.
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He's also someone who's a
cunning military strategist.
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- [Laurence] Alexander's army
defeats Persia in 331 BCE,
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and he's just getting started.
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- In 10 years,
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he conquers about two million
square miles of territory.
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It is the greatest empire
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that had ever been
seen at that time.
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- [Darel] But as Alexander
conquers this vast territory,
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he changes,
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he becomes removed
from his own soldiers.
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He begins to dress differently,
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wearing luxurious robes and
the crown of a Persian king
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and even begins to think
of himself as a God.
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- [Laurence] But in 324 BCE,
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a tragic event brings
Alexander down to earth.
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- [Hugo] Alexander's army
is marching east
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when his close friend
Hephaestion falls ill.
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Now, Alexander calls his doctor
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and demands that he
make Hephaestion well,
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threatening him if he doesn't.
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- [Nicola] After about a week,
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Hephaestion rallies, he
seems to be getting better.
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And when they present
him with some food,
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he immediately starts going
into convulsions and he dies.
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For Alexander, this
tears him apart.
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He's so overcome with grief
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that he falls down on
Hephaestion's body.
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He clings to his corpse for days
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until the generals
manage to wrench him off.
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- [Laurence] After the funeral,
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the Greek army continues
marching west towards Babylon,
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the empire's new capital.
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But Alexander remains
grief-stricken
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and now obsessed with
his own mortality.
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- [Darel] As Alexander
is returning
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to the city of Babylon,
right before entering the city,
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they see ravens
fighting in the sky
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and several of them drop
dead right at his feet.
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Now, the actions of
birds are often seen
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as an omen of future events,
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and having them fighting and
dying is seen as a bad omen,
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which made him paranoid.
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- [Hugo] He acquires a seer,
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to have an animal
sacrifice performed,
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and the goal is to find out
from the insides of the animal
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what your fate will be.
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Well, the seer notes
that death is lurking
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for someone powerful
inside Babylon,
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and Alexander is convinced
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that he's the person
this omen is meant for.
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- [Laurence] Once
inside the city walls,
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Alexander seeks distraction
from his growing fears.
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He finds it in alcohol.
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- [Adam] By the time they
get to Babylon,
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the army, or at least
what's left of it,
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are in a celebratory mood.
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And so we're talking
about a lot of partying,
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drinking fests going on
for days, weeks even,
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and Alexander is fully
immersed in this.
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- For the Greeks, everything
was a chance to have a contest.
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The king has to be best,
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he has to be the best
fighter, the best hunter,
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and he needs to be
the best drinker.
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And so Alexander would
get involved sometimes
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in these drinking contests,
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and they were imbibing a
fair amount of alcohol.
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- At one of these parties,
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Alexander consumes this
massive bowl of wine,
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and almost immediately
after doing so,
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he gets these acute abdominal
pains, doubles over,
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and a really high fever.
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- [Robert] All of the advisors
are beginning
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to get a little worried
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because they've just fought
to create this great kingdom
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and Alexander the Great
doesn't have an heir.
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And they all wanna know
who's gonna take over
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in the event that
Alexander dies.
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- They ask him over
and over again,
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"Who is gonna be
your successor?"
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And for the most part, he
just refuses to answer them.
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Finally, with one small breath,
he says, "To the strongest."
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- [Laurence] Not long after,
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the great conqueror dies
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without any official
pronouncement
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of what did him in.
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- [Darel] After all these years
of campaigning and severe wounds
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and all the stress
and the exhaustion,
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here he makes it back to
Babylon and then suddenly dies.
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One potential cause, therefore,
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might have been all that
partying and drinking.
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[dramatic music]
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- [Adam] As Alexander and
his army move east,
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he becomes increasingly paranoid
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that someone might try
to assassinate him.
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One of the ways that he
deals with this paranoia
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is by drinking.
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- Alexander's fear grows
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after an assassination attempt
that involved Philotas,
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the son of Parmenio, one
of his closest advisors.
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- Apparently Philotas had known
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that there was a
conspiracy afoot.
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He had heard rumors,
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and yet he did not
report this to Alexander.
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- [Nicola] Alexander gets wind
of the assassination plot
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and he goes
absolutely ballistic.
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He has Philotas killed
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and he actually has
Parmenio killed too.
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And Parmenio is really an
innocent bystander in this.
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It's his son, but he
doesn't know anything
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about this assassination plot.
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- [Darel] This means that
no one is safe.
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Anybody could be
implicated in a conspiracy,
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anybody could be killed.
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- [Laurence] From this point on,
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Alexander is said to experience
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uncontrollable fits
of anger and remorse,
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usually followed by drinking
binges that last days
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and sometimes turn deadly.
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- Alexander the Great has
a friend named Cleitus,
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one of his companions in battle,
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who actually saved Alexander's
life several times.
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Cleitus is trying to
give him some advice
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and he says, "Now that
you've defeated the Persians,
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you should be following the
Macedonian traditional customs
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and not these Persian customs."
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And Alexander gets so mad
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that he actually takes a pike
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and runs it through
Cleitus and kills him.
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- Alexander, though, is
immediately distraught,
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he can't believe what he's done.
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He locks himself in his
room for several days.
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He calls himself a murderer,
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feeling tremendous
guilt and shame.
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- Modern people would
look at this and say,
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this is classic
alcoholic behavior.
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We're talking about
drinking leads to violence,
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leads to grief, to shame.
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He is volatile,
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he is dangerous,
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and for anyone around him,
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they risk his wrath simply
by saying the wrong thing.
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- [Laurence] Now in Babylon
with little to occupy his time
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and many of his closest
companions dead,
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Alexander's unrestrained
drinking consumes him.
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- [Robert] Very few of his
advisors wanna stop him
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for fear of losing
their own heads,
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but his doctors do
come in and say,
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"Look, you have to stop
drinking alcohol here.
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Just drink some water."
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- [Darel] Instead of
getting better,
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Alexander is spiraling downward.
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And even though he's
tremendously thirsty,
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he wants more wine.
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- [Hugo] Consuming excessive
amounts of alcohol
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without ever drinking water
can lead to a condition
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that's called acute
necrotizing pancreatitis.
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This is a condition
where the pancreas rots
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as it's overwhelmed
with alcohol,
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and so this can lead to pain,
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it can lead to paralysis,
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and ultimately death.
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- [Laurence] For many scholars,
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alcohol poisoning remains
the most likely cause
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of Alexander's slow
and agonizing death,
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but others say
it's not so simple.
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- [Robert] It could have been
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that Alexander the Great
drank himself to death,
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but maybe it wasn't something
that Alexander did to himself,
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maybe something
malicious took place.
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- 323 BCE.
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Alexander the Great,
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one of the ancient world's
most victorious leaders,
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is dead at 32.
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As soon as the
news is announced,
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accusations fly about
who is responsible.
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- [Adam] If anyone could have
seen Alexander's death coming,
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it might have been him.
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In fact, in his final years,
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he sees plots everywhere,
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and so if someone
were to kill him,
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they would have to be
within his very small circle
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of trusted confidants.
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- Very few Macedonian kings
died of old age in their beds.
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Most of them died
with their boots on
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and some of them died
from assassination,
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so conspiracies against the
king certainly weren't uncommon.
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- The reality, though, is it's
really hard to murder a king,
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especially one who's
doing everything they can
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to protect themselves from
precisely that outcome.
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Even Alexander's
own trusted advisors
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were having trouble
accessing him.
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- There's really only one person
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who would be able to
get that close to him,
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that's the person who
shares his bed chamber.
254
00:12:15,691 --> 00:12:17,518
- [Laurence] While fighting
n Bactria,
255
00:12:17,519 --> 00:12:20,042
near present-day Afghanistan,
256
00:12:20,043 --> 00:12:23,306
Alexander becomes
infatuated with Roxana,
257
00:12:23,307 --> 00:12:26,745
the beautiful daughter
of a defeated king.
258
00:12:26,746 --> 00:12:28,050
- Scholars have debated
259
00:12:28,051 --> 00:12:30,618
about exactly what she
means for Alexander,
260
00:12:30,619 --> 00:12:33,752
with many saying that in fact
she was the love of his life.
261
00:12:33,753 --> 00:12:35,928
Alternatively, she could
have just been a pawn
262
00:12:35,929 --> 00:12:38,669
in a political game
to cement an alliance.
263
00:12:38,670 --> 00:12:42,935
In either case, Roxana
is incredibly ruthless
264
00:12:42,936 --> 00:12:45,589
and capable in her own right.
265
00:12:45,590 --> 00:12:48,157
- [Robert] You have to think
through her eyes for a second.
266
00:12:48,158 --> 00:12:51,900
Alexander has just defeated
her father and her family,
267
00:12:51,901 --> 00:12:55,077
and now he's literally
taking her as his wife,
268
00:12:55,078 --> 00:12:58,341
so she doesn't necessarily
like this arrangement.
269
00:12:58,342 --> 00:13:02,476
And then he's got this
best friend, Hephaestion,
270
00:13:02,477 --> 00:13:05,827
and maybe she's a
little jealous of him.
271
00:13:05,828 --> 00:13:10,310
- For many years, Hephaestion
is Alexander's closest friend
272
00:13:10,311 --> 00:13:12,094
and probably his lover.
273
00:13:12,095 --> 00:13:15,489
And when Hephaestion falls ill,
274
00:13:15,490 --> 00:13:18,753
Alexander brings his doctors
in to try to treat him,
275
00:13:18,754 --> 00:13:21,234
he gets better temporarily,
276
00:13:21,235 --> 00:13:23,627
but then when he
consumes a meal,
277
00:13:23,628 --> 00:13:27,022
he suddenly convulses and dies.
278
00:13:27,023 --> 00:13:29,372
- [Laurence] Some
historians remain convinced
279
00:13:29,373 --> 00:13:33,768
that these details point
to one thing, poison.
280
00:13:33,769 --> 00:13:35,291
- [Hugo] According
to some scholars,
281
00:13:35,292 --> 00:13:38,991
there was only one person in
Alexander's innermost circle
282
00:13:38,992 --> 00:13:40,862
who would have had the nerve
283
00:13:40,863 --> 00:13:44,300
to have actually executed
someone like Hephaestion,
284
00:13:44,301 --> 00:13:46,215
that would've been Roxana.
285
00:13:46,216 --> 00:13:49,784
- [Adam] She has the know-how
and the access,
286
00:13:49,785 --> 00:13:53,701
and so perhaps she
poisoned his friend
287
00:13:53,702 --> 00:13:56,051
to secure her position.
288
00:13:56,052 --> 00:13:58,140
If she's willing to do that,
289
00:13:58,141 --> 00:14:01,014
then what's to stop her
from poisoning Alexander?
290
00:14:02,015 --> 00:14:04,844
[dramatic music]
291
00:14:06,976 --> 00:14:10,283
- [Darel] Alexander and
Roxana are very close.
292
00:14:10,284 --> 00:14:11,893
She travels with him everywhere.
293
00:14:11,894 --> 00:14:15,027
In fact, he takes her on
his subsequent campaigning
294
00:14:15,028 --> 00:14:17,856
in Afghanistan and
even into India.
295
00:14:17,857 --> 00:14:19,292
This is very unusual,
296
00:14:19,293 --> 00:14:23,035
this is not something
Greeks and Macedonians do.
297
00:14:23,036 --> 00:14:26,473
- Roxana poses another
really important threat
298
00:14:26,474 --> 00:14:30,259
to the Macedonian throne in
that if she becomes pregnant,
299
00:14:30,260 --> 00:14:33,654
she will produce a
half-Bactrian offspring,
300
00:14:33,655 --> 00:14:37,049
which could be a real
legitimacy problem
301
00:14:37,050 --> 00:14:41,401
for those who want him to
have a purely Macedonian heir.
302
00:14:41,402 --> 00:14:43,229
- [Laurence] But
after the war is won
303
00:14:43,230 --> 00:14:46,145
and Alexander and
his wife march home,
304
00:14:46,146 --> 00:14:49,061
their special bond
begins to fray.
305
00:14:49,062 --> 00:14:50,149
- [Adam] On his way home,
306
00:14:50,150 --> 00:14:52,368
Alexander visits
the Persian kingdom
307
00:14:52,369 --> 00:14:54,805
in order to consolidate
his territory.
308
00:14:54,806 --> 00:14:56,286
While there,
309
00:14:56,373 --> 00:14:58,461
he marries the daughter
of the dead Persian king,
310
00:14:58,462 --> 00:15:00,550
her name is Stateira.
311
00:15:00,551 --> 00:15:04,380
Immediately she becomes
a threat to Roxana.
312
00:15:04,381 --> 00:15:08,167
Two women, both capable
of producing male sons,
313
00:15:08,168 --> 00:15:12,084
one of them is gonna have
her son succeed, not both.
314
00:15:12,085 --> 00:15:14,260
- [Laurence] Some
historians theorize
315
00:15:14,261 --> 00:15:18,090
that Roxana could be
behind Alexander's death,
316
00:15:18,091 --> 00:15:22,181
especially if the king
decides that Stateira's child,
317
00:15:22,182 --> 00:15:24,487
who is of more noble ancestry,
318
00:15:24,488 --> 00:15:28,230
should inherit the
throne and not Roxana's.
319
00:15:28,231 --> 00:15:31,146
- [Robert] Let's remember
that the progression
320
00:15:31,147 --> 00:15:35,194
of Hephaestion's symptoms
and ultimate death
321
00:15:35,195 --> 00:15:37,761
are similar to Alexander's.
322
00:15:37,762 --> 00:15:40,286
If it was a poisoning,
323
00:15:40,287 --> 00:15:43,767
it's possible that the same
poison may have been used
324
00:15:43,768 --> 00:15:44,987
to kill them both.
325
00:15:45,988 --> 00:15:47,771
- [Jeanne] At the time of
Alexander's death,
326
00:15:47,772 --> 00:15:50,035
both these women are pregnant.
327
00:15:50,036 --> 00:15:54,300
And for women in a
polygamous situation,
328
00:15:54,301 --> 00:15:56,084
their main ties are
not to their husbands,
329
00:15:56,085 --> 00:15:57,651
but to their children,
330
00:15:57,652 --> 00:15:59,870
that's how they stay alive.
331
00:15:59,871 --> 00:16:00,915
- [Hugo] According
to Plutarch,
332
00:16:00,916 --> 00:16:02,612
after Alexander dies,
333
00:16:02,613 --> 00:16:05,311
Roxana sends a
letter to Stateira,
334
00:16:05,312 --> 00:16:08,314
but she signs it under
the name of Alexander.
335
00:16:08,315 --> 00:16:11,534
It instructs Stateira
to go to Babylon.
336
00:16:11,535 --> 00:16:13,145
When she arrives,
337
00:16:13,146 --> 00:16:17,062
both her and her unborn child
are immediately slaughtered
338
00:16:17,063 --> 00:16:19,281
and their bodies are
thrown into a well
339
00:16:19,282 --> 00:16:21,109
and covered with earth.
340
00:16:21,110 --> 00:16:24,852
- [Laurence] It's an epic
tale of jealousy and betrayal,
341
00:16:24,853 --> 00:16:28,116
but to many it doesn't
stand up to scrutiny.
342
00:16:28,117 --> 00:16:29,944
- Roxana would have
a lot of trouble
343
00:16:29,945 --> 00:16:32,512
going back to Greece
without Alexander
344
00:16:32,513 --> 00:16:35,906
because there are many
native Macedonians
345
00:16:35,907 --> 00:16:38,257
who could very easily
take up the mantle
346
00:16:38,258 --> 00:16:39,736
of Alexander's kingship,
347
00:16:39,737 --> 00:16:43,914
and she would have no
stake in continuing
348
00:16:43,915 --> 00:16:47,222
to represent Alexander
if she was alone.
349
00:16:47,223 --> 00:16:49,572
- [Robert] Without the
protection of Alexander,
350
00:16:49,573 --> 00:16:51,357
she's a sitting duck.
351
00:16:51,358 --> 00:16:54,882
And so once he's dead,
352
00:16:54,883 --> 00:16:59,495
it wouldn't take much for
any of the rival generals
353
00:16:59,496 --> 00:17:01,803
to then turn around
and have her killed.
354
00:17:06,329 --> 00:17:08,635
- [Laurence] In 323 BCE,
355
00:17:08,636 --> 00:17:11,246
Alexander the Great
rules over an empire
356
00:17:11,247 --> 00:17:13,466
that spans three continents,
357
00:17:13,467 --> 00:17:17,644
but he neglects to do one
final thing before he dies,
358
00:17:17,645 --> 00:17:19,559
name a successor.
359
00:17:19,560 --> 00:17:22,214
- [Darel] Remember,
Alexander's last words
360
00:17:22,215 --> 00:17:26,653
when asked to whom did
he leave his empire were,
361
00:17:26,654 --> 00:17:28,307
"To the strongest."
362
00:17:28,308 --> 00:17:31,310
So it wouldn't be
a stretch to think
363
00:17:31,311 --> 00:17:34,095
that one of his close associates
364
00:17:34,096 --> 00:17:37,707
would try to be the strongest,
get rid of Alexander,
365
00:17:37,708 --> 00:17:39,319
and take over the empire.
366
00:17:40,407 --> 00:17:42,016
- [Hugo] According to several
ancient sources,
367
00:17:42,017 --> 00:17:46,542
Alexander's own mother
has, quote, "Sound proof"
368
00:17:46,543 --> 00:17:49,893
that somebody in
Alexander's inner circle
369
00:17:49,894 --> 00:17:52,071
was trying to poison him.
370
00:17:53,768 --> 00:17:56,552
- [Laurence] One name quickly
comes under suspicion.
371
00:17:56,553 --> 00:18:00,513
- If anyone out there thinks
that they have rightful claim
372
00:18:00,514 --> 00:18:01,818
to Alexander's empire,
373
00:18:01,819 --> 00:18:05,170
it would be the person
who is back in Greece
374
00:18:05,171 --> 00:18:07,824
essentially keeping
the throne warm
375
00:18:07,825 --> 00:18:10,871
while Alexander's
off on his exploits.
376
00:18:10,872 --> 00:18:13,614
[dramatic music]
377
00:18:15,746 --> 00:18:17,399
- [Darel] While Alexander
was away,
378
00:18:17,400 --> 00:18:20,750
campaigning in Asia
for some 11 years,
379
00:18:20,751 --> 00:18:24,232
he had left Greece
under the watchful eye
380
00:18:24,233 --> 00:18:26,496
of a regent named Antipater.
381
00:18:27,802 --> 00:18:30,934
- [Adam] Antipater came to power
as one of Philip II,
382
00:18:30,935 --> 00:18:33,023
Alexander's father's generals.
383
00:18:33,024 --> 00:18:34,808
Antipater, in his mind,
384
00:18:34,809 --> 00:18:38,333
has been running things for
Alexander for the last 10 years.
385
00:18:38,334 --> 00:18:41,467
He should be in power
if Alexander's dead.
386
00:18:41,468 --> 00:18:43,121
Alexander never saw it that way.
387
00:18:43,122 --> 00:18:45,601
In his mind,
Antipater's handling of
388
00:18:45,602 --> 00:18:46,863
the Greek city-states
389
00:18:46,864 --> 00:18:49,649
is a minor issue
next to this glory
390
00:18:49,650 --> 00:18:53,219
that Alexander has seized
for himself in Persia.
391
00:18:54,481 --> 00:18:56,090
- [Hugo] Antipater might have
expected
392
00:18:56,091 --> 00:18:59,006
that eventually this
man will fall in battle
393
00:18:59,007 --> 00:19:02,444
and that he'll have an
easy path to succession.
394
00:19:02,445 --> 00:19:06,013
So when Alexander conquers
Babylon and Persia
395
00:19:06,014 --> 00:19:09,451
and now is preparing to come
back to Greece a victor,
396
00:19:09,452 --> 00:19:13,238
Antipater knows that
his time is running out.
397
00:19:13,239 --> 00:19:17,067
- [Robert] The idea would be to
do it while he's still away,
398
00:19:17,068 --> 00:19:19,940
maybe while he's still
celebrating, while he's weak,
399
00:19:19,941 --> 00:19:22,160
while he's not paying attention,
400
00:19:22,161 --> 00:19:24,815
and so the place to do
this would be Babylon.
401
00:19:25,903 --> 00:19:28,340
- [Adam] If Antipater is
gonna make his move,
402
00:19:28,341 --> 00:19:29,776
it's gotta be now.
403
00:19:29,777 --> 00:19:31,299
And in fact,
404
00:19:31,300 --> 00:19:35,347
with Alexander drinking
himself into a bloody stupor,
405
00:19:35,348 --> 00:19:36,740
now is the perfect time.
406
00:19:38,916 --> 00:19:41,179
- [Laurence] But Antipater
can't knock off his rival
407
00:19:41,180 --> 00:19:42,136
in person,
408
00:19:42,137 --> 00:19:44,530
there are too many eyes on him.
409
00:19:44,531 --> 00:19:48,447
Instead, some historians
believe the general sends
410
00:19:48,448 --> 00:19:52,146
one of his sons to do
his dirty work for him.
411
00:19:52,147 --> 00:19:54,801
All it will take
is a dash of poison
412
00:19:54,802 --> 00:19:58,021
and Alexander never
leaves Babylon.
413
00:19:58,022 --> 00:20:02,635
It's a clever plan if
Antipater's son can pull it off.
414
00:20:02,636 --> 00:20:05,072
- Alexander, at this
point, is quite paranoid
415
00:20:05,073 --> 00:20:06,726
about conspiracies,
416
00:20:06,727 --> 00:20:08,641
so it's gonna be pretty hard
417
00:20:08,642 --> 00:20:12,559
for somebody to smuggle
poison into the palace.
418
00:20:13,473 --> 00:20:14,995
- [Adam] In order
for this to work,
419
00:20:14,996 --> 00:20:19,391
it would have to be a very
small amount of a lethal poison.
420
00:20:19,392 --> 00:20:21,784
This poison would
have to be so potent
421
00:20:21,785 --> 00:20:24,918
that it would do
the job in one dose.
422
00:20:24,919 --> 00:20:27,094
- [Laurence] There
is an ancient poison
423
00:20:27,095 --> 00:20:29,575
that perfectly fits
this description.
424
00:20:29,576 --> 00:20:34,057
- Alexander has a decline
that moves progressively.
425
00:20:34,058 --> 00:20:36,234
It begins with stomach pains,
426
00:20:36,235 --> 00:20:40,107
then he begins to experience
a complete lack of energy.
427
00:20:40,108 --> 00:20:42,588
His heart rate slows,
428
00:20:42,589 --> 00:20:45,895
then he slips into
a coma and dies.
429
00:20:45,896 --> 00:20:48,811
- [Nicola] Scientists and
historians have come up
430
00:20:48,812 --> 00:20:52,075
with one potential poison
431
00:20:52,076 --> 00:20:57,168
that seems to match what it
was that Alexander suffered.
432
00:20:57,908 --> 00:21:01,607
It's a small plant
called Veratrum album,
433
00:21:01,608 --> 00:21:05,045
and a little bit of this
plant goes a really long way.
434
00:21:05,046 --> 00:21:10,006
All it would take would be a
tiny drop of poison in his cup
435
00:21:10,007 --> 00:21:11,661
and it would all be over.
436
00:21:13,228 --> 00:21:15,098
- [Laurence] But
there's one key symptom
437
00:21:15,099 --> 00:21:17,449
Veratrum album doesn't cause,
438
00:21:17,450 --> 00:21:19,712
something mentioned in
nearly every account
439
00:21:19,713 --> 00:21:21,757
of Alexander's death,
440
00:21:21,758 --> 00:21:23,542
a high fever.
441
00:21:23,543 --> 00:21:24,934
- [Hugo] Historians theorize
442
00:21:24,935 --> 00:21:28,068
that another poison could
have also been used.
443
00:21:28,069 --> 00:21:29,722
It's a little known poison
444
00:21:29,723 --> 00:21:33,029
that would account for all
of Alexander's symptoms,
445
00:21:33,030 --> 00:21:36,946
it also is found
along the River Styx.
446
00:21:36,947 --> 00:21:38,687
- [Adam] In Greek mythology,
447
00:21:38,688 --> 00:21:39,862
the River Styx,
448
00:21:39,863 --> 00:21:41,951
besides being a gateway
to the underworld,
449
00:21:41,952 --> 00:21:44,606
is also the place
where the God Zeus
450
00:21:44,607 --> 00:21:47,783
has all the other gods
swear oaths to him.
451
00:21:47,784 --> 00:21:51,396
If they lie, he makes them
drink from the River Styx
452
00:21:51,397 --> 00:21:54,137
and they can't speak,
they can't move,
453
00:21:54,138 --> 00:21:55,531
they can't do anything.
454
00:21:56,837 --> 00:21:58,533
- [Laurence] Modern
toxicologists believe
455
00:21:58,534 --> 00:22:01,319
there's truth
behind this legend.
456
00:22:01,320 --> 00:22:04,017
- The River Styx is
a mythological river,
457
00:22:04,018 --> 00:22:05,758
but is often identified
458
00:22:05,759 --> 00:22:09,457
with the Mavroneri River
on the Greek Peloponnese.
459
00:22:09,458 --> 00:22:12,373
And in this river
there is a bacteria
460
00:22:12,374 --> 00:22:15,158
that grows there
called calicheamicin,
461
00:22:15,159 --> 00:22:20,208
and when ingested can lead
to paralysis and then death.
462
00:22:21,818 --> 00:22:25,430
And one of the things
about calicheamicin
463
00:22:25,431 --> 00:22:28,520
is that it causes high fever.
464
00:22:28,521 --> 00:22:32,480
- [Darel] It would be easy to
smuggle calicheamicin
465
00:22:32,481 --> 00:22:34,439
into Alexander's palace
466
00:22:34,440 --> 00:22:38,051
because it's basically
in the form of water,
467
00:22:38,052 --> 00:22:40,270
and so bringing
in a jug of water
468
00:22:40,271 --> 00:22:42,448
would be completely
above suspicion.
469
00:22:43,274 --> 00:22:46,538
- [Adam] There's no definitive
smoking gun evidence
470
00:22:46,539 --> 00:22:47,887
that it was Antipater,
471
00:22:47,888 --> 00:22:51,412
but his actions after
Alexander's death
472
00:22:51,413 --> 00:22:54,720
do suggest a certain
amount of ruthlessness.
473
00:22:54,721 --> 00:22:57,287
In addition to
immediately
474
00:22:57,288 --> 00:22:58,941
consolidating his
hold on Greece,
475
00:22:58,942 --> 00:23:04,077
he also summons Roxana
and her son back to him,
476
00:23:04,078 --> 00:23:06,514
throws them in a dungeon,
477
00:23:06,515 --> 00:23:10,083
and ultimately, his
henchman murder them.
478
00:23:10,084 --> 00:23:13,260
- [Laurence] Not everyone
agrees that Antipater would risk
479
00:23:13,261 --> 00:23:15,871
sending his son and
heir to the banquet,
480
00:23:15,872 --> 00:23:20,180
especially considering that
Alexander deeply mistrusts him.
481
00:23:20,181 --> 00:23:23,357
- [Jennifer] All of our major
sources on Alexander's death
482
00:23:23,358 --> 00:23:26,839
acknowledge this rumor that
Antipater is somehow involved,
483
00:23:26,840 --> 00:23:30,364
but it's very difficult
to disentangle
484
00:23:30,365 --> 00:23:32,061
what is the truth and what isn't
485
00:23:32,062 --> 00:23:36,065
because the struggles
between Alexander's generals
486
00:23:36,066 --> 00:23:39,678
in the division of his
empire following his death.
487
00:23:39,679 --> 00:23:41,636
- [Jeanne] In the
successor wars,
488
00:23:41,637 --> 00:23:44,117
it got so
incredibly nasty.
489
00:23:44,118 --> 00:23:47,294
You wanted to blacken the
name of your opponents,
490
00:23:47,295 --> 00:23:51,254
and so this appears to have
been a story that is fostered
491
00:23:51,255 --> 00:23:53,867
by another side in this fight.
492
00:23:59,089 --> 00:24:00,047
- While the citizens
of Greece are shocked
493
00:24:00,177 --> 00:24:01,917
by Alexander the
Great's sudden death,
494
00:24:01,918 --> 00:24:04,746
the king had feared
it for years.
495
00:24:04,747 --> 00:24:09,011
By the time he arrives
in Babylon in 323 BCE,
496
00:24:09,012 --> 00:24:11,144
Alexander is so paranoid
497
00:24:11,145 --> 00:24:13,929
that the list of people
who can get close to him
498
00:24:13,930 --> 00:24:15,627
is very short.
499
00:24:15,628 --> 00:24:19,065
At the top of that list is
his most trusted friend,
500
00:24:19,066 --> 00:24:22,372
and some say the man
with the most to gain
501
00:24:22,373 --> 00:24:24,811
by getting his king
out of the way.
502
00:24:26,073 --> 00:24:29,292
- [Darel] One of Alexander's
closest associates is Ptolemy.
503
00:24:29,293 --> 00:24:31,207
He had grown up with Alexander,
504
00:24:31,208 --> 00:24:34,210
been educated with
him, trained with him,
505
00:24:34,211 --> 00:24:38,519
and he was there by his side
through the whole campaign.
506
00:24:38,520 --> 00:24:41,740
- [Robert] This was a general
that Alexander trusted,
507
00:24:41,741 --> 00:24:45,047
he was essentially
his right-hand man.
508
00:24:45,048 --> 00:24:47,354
So maybe Ptolemy is
thinking to himself,
509
00:24:47,355 --> 00:24:50,183
if anybody's gonna take
over, it's gonna be me.
510
00:24:50,184 --> 00:24:52,011
- Alexander treats
him like a brother,
511
00:24:52,012 --> 00:24:56,885
so if he's the one who's
behind this suspicious death,
512
00:24:56,886 --> 00:25:00,149
Alexander would never
have even seen it coming.
513
00:25:00,150 --> 00:25:02,892
[dramatic music]
514
00:25:04,807 --> 00:25:08,114
- [Laurence] Ptolemy's insider
knowledge of future campaigns
515
00:25:08,115 --> 00:25:12,771
may give him a strong motive
for ending Alexander's reign.
516
00:25:12,772 --> 00:25:15,556
After a decade of
relentless war,
517
00:25:15,557 --> 00:25:18,646
Ptolemy and his army
have had enough.
518
00:25:18,647 --> 00:25:20,648
- [Jennifer] Alexander and his
men saw everything
519
00:25:20,649 --> 00:25:24,434
you could possibly imagine
over the course of this decade,
520
00:25:24,435 --> 00:25:28,351
arid desert, famine, monsoons,
521
00:25:28,352 --> 00:25:30,571
winter in the mountains,
522
00:25:30,572 --> 00:25:32,834
and it would have
worn these men down
523
00:25:32,835 --> 00:25:35,358
to an unimaginable degree.
524
00:25:35,359 --> 00:25:37,578
- Once they get to India,
525
00:25:37,579 --> 00:25:39,754
Alexander wants to keep going,
526
00:25:39,755 --> 00:25:41,539
but his men have other ideas.
527
00:25:41,540 --> 00:25:44,933
In fact, they mutiny,
refusing to go further.
528
00:25:44,934 --> 00:25:48,502
In a rage, Alexander says he's
just gonna leave them behind.
529
00:25:48,503 --> 00:25:50,199
If they don't follow him,
530
00:25:50,200 --> 00:25:53,377
he's gonna keep going and take
all of the glory for himself.
531
00:25:54,683 --> 00:25:56,771
- [Nicolas] Once Alexander
realizes that even his
532
00:25:56,772 --> 00:25:58,947
own generals don't want to
continue the campaign,
533
00:25:58,948 --> 00:26:01,559
he retreats into his
tent for three days.
534
00:26:01,560 --> 00:26:03,691
- [Hugo] When he comes back out,
535
00:26:03,692 --> 00:26:06,520
he tells everyone that he's
communicated with the gods
536
00:26:06,521 --> 00:26:11,438
and they have told him that it
is unwise to advance further.
537
00:26:11,439 --> 00:26:14,267
- [Darel] Of course, this allows
Alexander to save face.
538
00:26:14,268 --> 00:26:17,009
He doesn't have to say,
well, I gave into the troops,
539
00:26:17,010 --> 00:26:19,707
they made me turn back,
540
00:26:19,708 --> 00:26:22,276
no, it was the
gods who did this.
541
00:26:23,843 --> 00:26:25,670
- [Robert] So now they're
back in Babylon.
542
00:26:25,671 --> 00:26:27,715
They've conquered
everything that you can,
543
00:26:27,716 --> 00:26:29,369
all of Western Asia.
544
00:26:29,370 --> 00:26:33,286
They've watched a lot of their
friends, their comrades, die
545
00:26:33,287 --> 00:26:34,809
and they wanna go home.
546
00:26:34,810 --> 00:26:36,768
- [Darel] Unfortunately
for his soldiers,
547
00:26:36,769 --> 00:26:38,770
Alexander is not finished.
548
00:26:38,771 --> 00:26:40,728
He doesn't want to just go home,
549
00:26:40,729 --> 00:26:43,513
he wants to embark on
another huge campaign,
550
00:26:43,514 --> 00:26:46,168
he wants to invade Arabia,
551
00:26:46,169 --> 00:26:49,303
and no one is particularly
eager to do that.
552
00:26:50,783 --> 00:26:55,308
- It might be at this point
that a man like Ptolemy steps in
553
00:26:55,309 --> 00:26:58,964
if only to save the
army from the commander.
554
00:26:58,965 --> 00:27:00,922
Already the men are broken,
555
00:27:00,923 --> 00:27:02,576
they don't wanna move on,
556
00:27:02,577 --> 00:27:04,143
but Alexander does.
557
00:27:04,144 --> 00:27:07,147
This is the time to put
a stop to all of this.
558
00:27:08,844 --> 00:27:11,672
- [Robert] So the idea would be
that maybe Ptolemy used a poison
559
00:27:11,673 --> 00:27:13,848
that wasn't super potent,
560
00:27:13,849 --> 00:27:17,112
but that killed over a
longer period of time.
561
00:27:17,113 --> 00:27:20,289
And a poison that
acted in this way
562
00:27:20,290 --> 00:27:23,642
that was readily
available is arsenic.
563
00:27:25,513 --> 00:27:27,470
- [Hugo] Arsenic is
found in soil and rock
564
00:27:27,471 --> 00:27:29,603
all over the world.
565
00:27:29,604 --> 00:27:32,519
It's tasteless
and it's odorless.
566
00:27:32,520 --> 00:27:36,305
It's a poison that works in
a very generalized manner
567
00:27:36,306 --> 00:27:37,742
across the body,
568
00:27:37,743 --> 00:27:41,093
and so people will
see physical symptoms,
569
00:27:41,094 --> 00:27:45,401
but not necessarily be able
to trace it to one cause.
570
00:27:45,402 --> 00:27:46,925
- [Nicola] An interesting
thing about arsenic
571
00:27:46,926 --> 00:27:49,101
is that it gets into the tissues
572
00:27:49,102 --> 00:27:52,582
and it slows the process
of decomposition.
573
00:27:52,583 --> 00:27:55,585
And one thing that the
ancient sources say
574
00:27:55,586 --> 00:28:00,155
is that Alexander's body took
a very long time to decay.
575
00:28:00,156 --> 00:28:03,158
- [Adam] But one has to
wonder whether Ptolemy,
576
00:28:03,159 --> 00:28:06,988
who is obviously traveling
on campaign like Alexander
577
00:28:06,989 --> 00:28:10,165
in much greater comfort
than an ordinary soldier,
578
00:28:10,166 --> 00:28:12,167
would've murdered his friend
579
00:28:12,168 --> 00:28:15,780
just because the army had
lost the will to fight.
580
00:28:15,781 --> 00:28:17,912
- [Laurence] Ancient
historians suggest
581
00:28:17,913 --> 00:28:20,219
that a more personal motivation
582
00:28:20,220 --> 00:28:24,702
may be behind Ptolemy's
desire to kill his king.
583
00:28:24,703 --> 00:28:27,008
- [Hugo] Alexander has never
named a successor,
584
00:28:27,009 --> 00:28:29,532
and there's a question of
who is going to follow him
585
00:28:29,533 --> 00:28:32,753
if anything happens to him
on the field of battle.
586
00:28:32,754 --> 00:28:35,538
Ptolemy might well
have wanted to ensure
587
00:28:35,539 --> 00:28:38,628
that he was the person
who would take over.
588
00:28:38,629 --> 00:28:40,587
- [Laurence] Some
believe Ptolemy's actions
589
00:28:40,588 --> 00:28:43,285
immediately after
Alexander's death
590
00:28:43,286 --> 00:28:47,420
suggest he played a role
in the king's demise.
591
00:28:47,421 --> 00:28:49,291
- [Jennifer] The body of
Alexander becomes
592
00:28:49,292 --> 00:28:52,164
a really important
ideological tool,
593
00:28:52,165 --> 00:28:57,125
and so his successors fight
over his body as a way to show
594
00:28:57,126 --> 00:29:00,520
that they are the real
chosen heir of Alexander.
595
00:29:00,521 --> 00:29:03,566
Ptolemy is the first
one to hijack the body
596
00:29:03,567 --> 00:29:06,352
and take it with him to Egypt.
597
00:29:06,353 --> 00:29:08,876
- [Darel] By bringing
Alexander's body to Egypt,
598
00:29:08,877 --> 00:29:11,749
Ptolemy is being quite
shrewd politically.
599
00:29:11,750 --> 00:29:14,055
This legitimizes not
only his reign in Egypt,
600
00:29:14,056 --> 00:29:17,755
but perhaps a claim to
Alexander's entire empire
601
00:29:17,756 --> 00:29:20,235
as the rightful successor.
602
00:29:20,236 --> 00:29:23,543
- [Adam] It also is a convenient
way to control the body
603
00:29:23,544 --> 00:29:26,067
and thus preclude
any possibility
604
00:29:26,068 --> 00:29:28,896
of people noticing
any suspicious signs
605
00:29:28,897 --> 00:29:30,811
of arsenic poisoning,
606
00:29:30,812 --> 00:29:33,945
if that's indeed
what Ptolemy did.
607
00:29:33,946 --> 00:29:37,383
- [Laurence] Not everyone is
on board with this theory.
608
00:29:37,384 --> 00:29:40,995
Many scholars contend that
Ptolemy has more to gain
609
00:29:40,996 --> 00:29:43,955
with Alexander alive than dead.
610
00:29:43,956 --> 00:29:48,307
- Alexander is leading the
army and Ptolemy has his ear.
611
00:29:48,308 --> 00:29:50,135
There's no clear
succession plan,
612
00:29:50,136 --> 00:29:52,354
and so if Ptolemy were
to plot his death,
613
00:29:52,355 --> 00:29:54,008
he would have no way of knowing
614
00:29:54,009 --> 00:29:57,185
whether he would end
up being the successor.
615
00:29:57,186 --> 00:30:00,841
- [Darel] Why take the risk of
assassinating Alexander
616
00:30:00,842 --> 00:30:03,191
when he could have
simply succeeded him
617
00:30:03,192 --> 00:30:06,456
had Alexander died of
other unusual causes?
618
00:30:10,721 --> 00:30:12,070
- [Laurence] After
Alexander the Great ends
619
00:30:12,071 --> 00:30:13,506
his military campaign,
620
00:30:13,507 --> 00:30:17,423
he seems eager to regain
the trust of his troops.
621
00:30:17,424 --> 00:30:21,601
Some historians wonder if
this desire may be behind
622
00:30:21,602 --> 00:30:24,343
his untimely sickness and death.
623
00:30:24,344 --> 00:30:26,519
- [Robert] When Alexander
gets to Babylon,
624
00:30:26,520 --> 00:30:30,349
he decides he's gonna
make this his new capital.
625
00:30:30,350 --> 00:30:34,266
For one, it's this
famous city in the east,
626
00:30:34,267 --> 00:30:37,269
two, it's much closer
to all of this land
627
00:30:37,270 --> 00:30:39,575
that he's just conquered.
628
00:30:39,576 --> 00:30:43,928
- Babylon is 2,000
years old at this time.
629
00:30:43,929 --> 00:30:45,886
It's a wonderful city,
630
00:30:45,887 --> 00:30:50,238
but it is also cramped and in
drastic need of renovation,
631
00:30:50,239 --> 00:30:54,068
and so Alexander immediately
inspects the defenses
632
00:30:54,069 --> 00:30:56,592
to make sure they are secure.
633
00:30:56,593 --> 00:30:57,898
- As a leader of men,
634
00:30:57,899 --> 00:31:00,074
he wants to be close
to his soldiers,
635
00:31:00,075 --> 00:31:02,120
so he goes out
there on inspections
636
00:31:02,121 --> 00:31:04,644
and he shows his soldiers
that he's not above them,
637
00:31:04,645 --> 00:31:07,125
that he's willing to
get his hands dirty.
638
00:31:07,126 --> 00:31:09,954
- [Laurence] Military
camps have long been known
639
00:31:09,955 --> 00:31:14,393
as breeding grounds for
all kinds of diseases.
640
00:31:14,394 --> 00:31:15,698
- In the Old Testament,
641
00:31:15,699 --> 00:31:17,787
there's a story about
a Mesopotamian king
642
00:31:17,788 --> 00:31:20,921
who lays siege to
the city of Jerusalem
643
00:31:20,922 --> 00:31:24,316
until a plague breaks
out in his camp,
644
00:31:24,317 --> 00:31:26,622
and suddenly the soldiers
are thrown into disarray
645
00:31:26,623 --> 00:31:29,234
and they stagger back home.
646
00:31:29,235 --> 00:31:32,454
- [Nicola] It makes sense that
if Alexander is out there
647
00:31:32,455 --> 00:31:34,717
walking around in the city,
648
00:31:34,718 --> 00:31:36,676
getting really close to people,
649
00:31:36,677 --> 00:31:40,506
that he would've been exposed
to very unsanitary conditions,
650
00:31:40,507 --> 00:31:43,813
the precise conditions
that would've given rise
651
00:31:43,814 --> 00:31:47,121
to some sort of
terrible illness.
652
00:31:47,122 --> 00:31:49,864
[dramatic music]
653
00:31:52,736 --> 00:31:55,042
- [Adam] History's earliest
mention of an epidemic
654
00:31:55,043 --> 00:31:58,480
actually comes from a
Mesopotamian tablet.
655
00:31:58,481 --> 00:32:01,005
It's a medical record that
lists the cause of death
656
00:32:01,006 --> 00:32:02,963
of the people on the tablet,
657
00:32:02,964 --> 00:32:05,705
and it uses a word that
most scholars translate
658
00:32:05,706 --> 00:32:08,969
to either be plague
or pestilence.
659
00:32:08,970 --> 00:32:11,624
- In Alexander's home
country of Greece,
660
00:32:11,625 --> 00:32:14,409
there was a plague
that is believed
661
00:32:14,410 --> 00:32:16,324
to have originated in Ethiopia,
662
00:32:16,325 --> 00:32:18,631
and it was carried
to Athens on ships
663
00:32:18,632 --> 00:32:22,200
and it killed about 1/3
of the entire population.
664
00:32:22,201 --> 00:32:25,072
- Some scholars think that
this might have been a variant
665
00:32:25,073 --> 00:32:26,639
to bubonic plague.
666
00:32:26,640 --> 00:32:29,859
Others think that this might
have been typhus or measles,
667
00:32:29,860 --> 00:32:32,037
both of which were
incurable in this period.
668
00:32:33,168 --> 00:32:35,126
- [Laurence] But there's
a more likely killer
669
00:32:35,127 --> 00:32:38,259
hiding in Alexander's
military camps.
670
00:32:38,260 --> 00:32:40,522
- [Nicolas] Today, the area
around the city of Babylon
671
00:32:40,523 --> 00:32:42,394
is this dry, arid desert,
672
00:32:42,395 --> 00:32:45,266
but in Alexander's time, it
would've been this marshland
673
00:32:45,267 --> 00:32:48,356
that was a breeding
ground for mosquitoes.
674
00:32:48,357 --> 00:32:50,837
- [Hugo] Some epidemiologists
have suggested
675
00:32:50,838 --> 00:32:54,841
that the true killer might
have been West Nile virus.
676
00:32:54,842 --> 00:32:56,712
- [Jannifer] In very
marshy conditions,
677
00:32:56,713 --> 00:32:59,411
West Nile virus is rife
678
00:32:59,412 --> 00:33:03,676
and it infects mosquitoes,
but also birds.
679
00:33:03,677 --> 00:33:08,420
And we know from the sources
that Alexander saw ravens
680
00:33:08,421 --> 00:33:10,161
that were fighting
with one another
681
00:33:10,162 --> 00:33:13,512
and then they just
collapsed dead at his feet,
682
00:33:13,513 --> 00:33:17,646
so they may have been
infected with West Nile virus.
683
00:33:17,647 --> 00:33:20,171
- [Nicolas] It's possible that
these waterborne mosquitoes
684
00:33:20,172 --> 00:33:23,087
contract the disease
from these ravens,
685
00:33:23,088 --> 00:33:24,566
and it's only a matter of time
686
00:33:24,567 --> 00:33:27,309
before it transfers to
the human population.
687
00:33:28,484 --> 00:33:30,050
- What's interesting
about West Nile virus
688
00:33:30,051 --> 00:33:32,400
is that its symptoms
mimic very closely
689
00:33:32,401 --> 00:33:34,141
what Alexander's symptoms were,
690
00:33:34,142 --> 00:33:37,231
so headaches, problems
with breathing,
691
00:33:37,232 --> 00:33:39,539
respiratory distress, and fever.
692
00:33:40,888 --> 00:33:42,715
- [Laurence]
Mosquitoes also carry
693
00:33:42,716 --> 00:33:44,630
an even more lethal threat,
694
00:33:44,631 --> 00:33:47,633
one of human history's
greatest mass murderers.
695
00:33:47,634 --> 00:33:52,116
- At one time, people speculated
that malaria had killed
696
00:33:52,117 --> 00:33:56,076
almost half the human
beings who had ever lived.
697
00:33:56,077 --> 00:33:58,252
While recent
reevaluations have said
698
00:33:58,253 --> 00:34:01,386
that statistic is
probably a bit overblown,
699
00:34:01,387 --> 00:34:04,606
malaria is still one
of the biggest killers
700
00:34:04,607 --> 00:34:06,348
of humans throughout history.
701
00:34:07,654 --> 00:34:10,395
- [Nicolas] Ancient texts from
Mesopotamia, Egypt, and Greece
702
00:34:10,396 --> 00:34:14,355
have described illnesses that
have malaria-like symptoms.
703
00:34:14,356 --> 00:34:16,444
And more recent
studies have even shown
704
00:34:16,445 --> 00:34:19,273
that malaria was present
in these populations
705
00:34:19,274 --> 00:34:21,971
at the time of
Alexander the Great.
706
00:34:21,972 --> 00:34:24,278
- [Adam] While there are
four types of malaria,
707
00:34:24,279 --> 00:34:27,673
only one, falciparum,
is especially fatal.
708
00:34:27,674 --> 00:34:30,589
The parasites develop
silently in the liver
709
00:34:30,590 --> 00:34:32,156
until they mature,
710
00:34:32,157 --> 00:34:35,985
and then they multiply and
invade the red blood cells.
711
00:34:35,986 --> 00:34:38,988
- [Laurence] The trajectory
of the disease closely mirrors
712
00:34:38,989 --> 00:34:41,252
the account of
Alexander's decline,
713
00:34:41,253 --> 00:34:43,471
and ultimately, his death.
714
00:34:43,472 --> 00:34:46,039
- Alexander dies in late May,
715
00:34:46,040 --> 00:34:50,130
and mosquitoes are most
active during this period
716
00:34:50,131 --> 00:34:52,307
of the late spring
and the early summer.
717
00:34:53,656 --> 00:34:56,223
- [Darel] When you consider the
incubation period of malaria
718
00:34:56,224 --> 00:34:57,485
of one to two weeks,
719
00:34:57,486 --> 00:34:59,096
that would fit with the timeline
720
00:34:59,097 --> 00:35:01,402
with Alexander
inspecting these camps,
721
00:35:01,403 --> 00:35:05,276
possibly even boating
in the marshes.
722
00:35:05,277 --> 00:35:06,538
- [Hugo] Writings of
the time also say
723
00:35:06,539 --> 00:35:08,931
that as Alexander becomes sick,
724
00:35:08,932 --> 00:35:11,934
his sleep patterns
are thrown way off,
725
00:35:11,935 --> 00:35:14,372
and this is a symptom
that's also consistent
726
00:35:14,373 --> 00:35:16,678
with falciparum malaria.
727
00:35:16,679 --> 00:35:18,680
- [Adam] Additionally,
malaria causes
728
00:35:18,681 --> 00:35:21,727
stabbing back pain, delirium.
729
00:35:21,728 --> 00:35:24,295
Both of those are things
that Alexander suffers from
730
00:35:24,296 --> 00:35:26,906
in his final days.
731
00:35:26,907 --> 00:35:28,168
- [Laurence] We also know
732
00:35:28,169 --> 00:35:31,084
that Alexander is
susceptible to malaria
733
00:35:31,085 --> 00:35:34,305
as he most likely
caught it once before.
734
00:35:34,306 --> 00:35:37,743
- The ancient records show
that when Alexander was 23,
735
00:35:37,744 --> 00:35:40,354
he did contract malaria,
736
00:35:40,355 --> 00:35:42,356
but he was young,
he was healthy.
737
00:35:42,357 --> 00:35:45,316
And so after two
months of bedrest,
738
00:35:45,317 --> 00:35:49,755
he recovered and went on to
become Alexander the Great.
739
00:35:49,756 --> 00:35:51,235
- [Darel] 10 years later,
740
00:35:51,236 --> 00:35:55,326
after fighting all these
battles, accumulation of wounds,
741
00:35:55,327 --> 00:35:56,979
excessive drinking,
742
00:35:56,980 --> 00:35:59,895
it's possible that
Alexander's body was not able
743
00:35:59,896 --> 00:36:03,551
to fight off the disease in
the way that it had before,
744
00:36:03,552 --> 00:36:05,250
and he ultimately
succumbed to it.
745
00:36:09,645 --> 00:36:11,080
- [Laurence] Before
Alexander the Great dies,
746
00:36:11,081 --> 00:36:14,171
he leaves three odd
instructions for his funeral.
747
00:36:14,172 --> 00:36:18,697
One, that his unsuccessful
doctors carry his coffin.
748
00:36:18,698 --> 00:36:21,526
Two, that his earthly
treasures be scattered
749
00:36:21,527 --> 00:36:23,484
along the way to his grave.
750
00:36:23,485 --> 00:36:28,446
And three, that his hand
swings free from his coffin.
751
00:36:28,447 --> 00:36:30,404
- [Robert] Alexander
could be saying,
752
00:36:30,405 --> 00:36:33,146
"Look, I'm mortal, I'm dying,
753
00:36:33,147 --> 00:36:35,017
all of the best doctors
couldn't save me,
754
00:36:35,018 --> 00:36:36,976
I'm not taking anything with me.
755
00:36:36,977 --> 00:36:39,588
Nobody could defeat
me, only death itself."
756
00:36:40,807 --> 00:36:43,417
- [Adam] Despite the oppressive
Mesopotamian heat,
757
00:36:43,418 --> 00:36:47,247
his body doesn't
decompose in a normal way.
758
00:36:47,248 --> 00:36:48,640
And so in fact,
759
00:36:48,641 --> 00:36:53,254
his followers increasingly
see him as a God.
760
00:36:55,125 --> 00:36:57,953
- [Hugo] Alexander had actually
been proclaimed a God
761
00:36:57,954 --> 00:37:01,566
by Oracles in
Greece and in Egypt.
762
00:37:01,567 --> 00:37:03,481
And so as someone divine,
763
00:37:03,482 --> 00:37:05,178
many people would've imagined
764
00:37:05,179 --> 00:37:09,530
that perhaps his body would
have never rotted or decayed,
765
00:37:09,531 --> 00:37:13,795
that it would in fact have
been preserved eternally.
766
00:37:13,796 --> 00:37:15,493
- [Laurence] But a
recent theory suggests
767
00:37:15,494 --> 00:37:19,845
that what these mourners are
witnessing is no miracle.
768
00:37:19,846 --> 00:37:23,109
- According to this
recent 2018 theory
769
00:37:23,110 --> 00:37:25,329
from a New Zealand researcher,
770
00:37:25,330 --> 00:37:28,767
Alexander was not
mummified magically,
771
00:37:28,768 --> 00:37:31,857
but was in fact
trapped in his body,
772
00:37:31,858 --> 00:37:35,818
unable to speak or even indicate
that he was still alive.
773
00:37:36,732 --> 00:37:39,605
[dramatic music]
774
00:37:41,998 --> 00:37:45,827
- [Hugo] Guillain-Barre syndrome
is a rare autoimmune disorder.
775
00:37:45,828 --> 00:37:49,309
It essentially causes
the body to be paralyzed,
776
00:37:49,310 --> 00:37:51,703
even as the mind
is still active.
777
00:37:51,704 --> 00:37:55,402
- The exact cause of this
disorder is actually unknown,
778
00:37:55,403 --> 00:37:58,579
but interestingly, scientists
have traced it back
779
00:37:58,580 --> 00:38:02,191
to a particular bacterium
called campylobacter.
780
00:38:02,192 --> 00:38:04,890
It's often in uncooked poultry,
781
00:38:04,891 --> 00:38:06,892
and if it's ingested,
782
00:38:06,893 --> 00:38:10,983
then it multiplies and it
ends up attacking the brain.
783
00:38:10,984 --> 00:38:13,377
- [Darel] The syndrome
progresses slowly.
784
00:38:13,378 --> 00:38:16,728
It first begins with
just a lack of energy,
785
00:38:16,729 --> 00:38:20,209
and then some sleep aberrations,
786
00:38:20,210 --> 00:38:23,561
but then you begin to get
numbness in the limbs,
787
00:38:23,562 --> 00:38:26,781
which eventually
develops into paralysis.
788
00:38:26,782 --> 00:38:29,393
- If the body is unable
to fight off the disease,
789
00:38:29,394 --> 00:38:31,395
then the brainstem
begins to fail.
790
00:38:31,396 --> 00:38:33,092
Heartbeat is going to slow,
791
00:38:33,093 --> 00:38:35,355
respiration is going to slow,
792
00:38:35,356 --> 00:38:38,576
almost to the point of people
thinking that they're gone.
793
00:38:38,577 --> 00:38:41,405
- [Robert] If this is what
happened to Alexander the Great,
794
00:38:41,406 --> 00:38:44,059
then what all of the ancient
doctors would've seen
795
00:38:44,060 --> 00:38:46,410
was a dead individual,
796
00:38:46,411 --> 00:38:50,589
but actually Alexander would've
been in a deep, deep coma.
797
00:38:51,938 --> 00:38:54,418
- [Laurence] This could
explain why Alexander's body
798
00:38:54,419 --> 00:38:57,638
doesn't decompose
for almost a week.
799
00:38:57,639 --> 00:39:01,381
- We don't know for sure
whether the mind is conscious
800
00:39:01,382 --> 00:39:04,166
or simply functioning
on a low level.
801
00:39:04,167 --> 00:39:07,909
However, those infected
could actually stay alive
802
00:39:07,910 --> 00:39:09,302
for several days,
803
00:39:09,303 --> 00:39:11,914
even though it appears
that they're dead.
804
00:39:13,002 --> 00:39:15,569
- [Nicola] Imagine if
Guillain-Barre syndrome
805
00:39:15,570 --> 00:39:18,224
is what Alexander suffered from.
806
00:39:18,225 --> 00:39:23,185
He may well have still
been alive and conscious
807
00:39:23,186 --> 00:39:26,580
and witnessing his own funeral.
808
00:39:26,581 --> 00:39:28,147
- [Laurence] Eventually,
809
00:39:28,148 --> 00:39:31,411
Alexander's brainstem would
stop working completely,
810
00:39:31,412 --> 00:39:33,675
this is when true death occurs.
811
00:39:34,676 --> 00:39:36,242
- [Jennifer] With
Guillain-Barre syndrome,
812
00:39:36,243 --> 00:39:40,028
one is comatose,
but still alive,
813
00:39:40,029 --> 00:39:41,813
potentially for almost a week.
814
00:39:41,814 --> 00:39:43,249
And after six days,
815
00:39:43,250 --> 00:39:46,645
Alexander's body does
finally start to decompose.
816
00:39:47,689 --> 00:39:49,777
- After Alexander's funeral,
817
00:39:49,778 --> 00:39:54,260
his vast kingdom that he
worked so hard to build up
818
00:39:54,261 --> 00:39:57,481
immediately begins to fracture.
819
00:39:57,482 --> 00:40:00,135
- [Hugo] Individual territories
start rebelling
820
00:40:00,136 --> 00:40:01,615
in the vacuum of power.
821
00:40:01,616 --> 00:40:04,183
His generals, wanting
to seize control,
822
00:40:04,184 --> 00:40:06,185
begin fighting with one another.
823
00:40:06,186 --> 00:40:09,188
And many different parts
of the empire will collapse
824
00:40:09,189 --> 00:40:10,495
within a few decades.
825
00:40:12,410 --> 00:40:15,847
- [Adam] Alexander did
more in 10 years
826
00:40:15,848 --> 00:40:18,327
than other people
do in lifetimes.
827
00:40:18,328 --> 00:40:20,068
It wouldn't be until
the Roman Empire
828
00:40:20,069 --> 00:40:21,983
that you would ever
see an empire as large,
829
00:40:21,984 --> 00:40:24,899
and that took hundreds of years.
830
00:40:24,900 --> 00:40:26,161
- [Darel] Alexander
was more than
831
00:40:26,162 --> 00:40:28,163
just a great military conquer.
832
00:40:28,164 --> 00:40:30,601
By unifying three continents,
833
00:40:30,602 --> 00:40:33,821
Europe, parts of
Africa, parts of Asia,
834
00:40:33,822 --> 00:40:36,563
it resulted in a
mixing of cultures
835
00:40:36,564 --> 00:40:39,218
that changed the
course of history.
836
00:40:39,219 --> 00:40:41,699
- [Nicola] Nobody has been able
to accomplish something
837
00:40:41,700 --> 00:40:44,658
like this either before
or since Alexander,
838
00:40:44,659 --> 00:40:48,446
and he did all this
before the age of 32.
839
00:40:52,580 --> 00:40:54,668
- Alexander the
Great is regarded
840
00:40:54,669 --> 00:40:58,759
as one of history's most
successful military leaders.
841
00:40:58,760 --> 00:41:03,024
He has inspired everyone from
Julius Caesar to Genghis Khan
842
00:41:03,025 --> 00:41:05,549
and Napoleon Bonaparte.
843
00:41:05,550 --> 00:41:06,854
Even today,
844
00:41:06,855 --> 00:41:09,857
Alexander's brilliant war
strategies are studied
845
00:41:09,858 --> 00:41:12,425
at West Point Military Academy,
846
00:41:12,426 --> 00:41:17,299
but how this iconic leader died
remains a perplexing riddle
847
00:41:17,300 --> 00:41:18,476
yet to be solved.
848
00:41:19,302 --> 00:41:20,912
I'm Laurence Fishburne.
849
00:41:20,913 --> 00:41:24,917
Thank you for watching
History's Greatest Mysteries.